Clinical Trial Case Studies

Discover how we have turned around clinical trials for our clients

Accelerating the patient enrollment rate in a global rare disease trial despite the COVID-19 pandemic

Rare Disease: A Phase IIa Lupus Case Study

A global pharmaceutical company instructed Innovative Trials to support them in screening 735 patients and enrolling 249 patients for a complex global Lupus (LSE) study. Innovative Trials deployed a ‘boot-on-the-ground’ approach via their Clinical Enrollment Managers (CEMs) to deliver Site Enrollment Optimization Support paired with study branding & development of patient recruitment materials, study website & prescreening creation, and digital campaign execution.

Increasing patient randomisation rate by 200% for a Top 5 global pharma

Phase IIa Moderate to Severe Hidradenitis Suppurativa Case Study

A Top 5 pharma was looking to randomise 192 patients with moderate to severe HS at 60 sites across the USA, Canada and Australia. Innovative Trials was asked to provide support with patient recruitment and demonstrated that a multi-faceted patient-centric recruitment strategy with a focus on optimising site engagement can overcome potential obstacles and deliver faster, more efficient results.

Clinical Enrolment Managers (CEMs) supported sites showed a 181% increase in pre-screening rates following calls.

Paediatric Case Study: Type II Diabetes Phase IIIa

The study sponsor approached Innovative Trials to aid recruitment activities on this Phase IIIa rescue study, where targets were not being met. Despite challenging inclusion criteria, this study saw success in recruiting children and adolescents with Type II Diabetes.

Sites receiving diversity outreach visits saw a 63% increase in randomised patients than those without.

Diversity Outreach Case Study: Active SLE Phase III

Innovative Trials’ services were rolled out to support the study sponsor with community outreach for this Phase III Active Systemic Lupus Erythematosus (SLE) study. The study looked to increase awareness access to clinical trials amongst diverse communities.

Clinical Enrolment Managers (CEMs) supported sites able to screen 73.2% more patients.

Paediatric Case Study: Moderate to Severe Atopic Dermatitis Phase III

The study sponsor approached Innovative Trials to support site enrolment for this phase 3 study in atopic dermatitis.

This particular study required children with moderate to severe atopic dermatitis, to trial an oral treatment, around their school schedules.

Innovative Trials’ Clinical Enrolment Managers (CEMs) enabled sites to significantly increase enrolment in a complex pancreatic cancer study.

Phase III germline BRCA mutated (gBRCAm) metastatic pancreatic cancer

Innovative Trials were approached by the study sponsor to boost enrolment for a phase 3 study in pancreatic cancer.

The study required patients with gBRCAm metastatic pancreatic cancer whose disease had not progressed on first line platinum based chemotherapy.

Rapid implementation of a 2-month rescue pilot led to a 113% increase in randomisation rates, getting the study back on schedule.

Rescue Case Study: Oncology Phase III

A leading biopharmaceutical company approached Innovative Trials to increase enrolment for their phase III study of Metastatic Colorectal Cancer (mCRC). The study needed to enroll 1250 eligible patients, however sites were experiencing severe enrolment fatigue and enrolment was lagging.

Community Outreach Boosted Enrolment for a Birth Control Study.

Community Outreach Case Study: Women’s Health Phase III

Innovative Trials were approached to support a mid size pharmaceutical company to accelerate enrolment for a Phase III birth control study in the US. The study needed to enrol 1357 healthy women aged 18-35 in a 7 month period.

Learn how we can make your clinical trial a success

Therapy Areas

We have extensive experience of study phases I to IV, adults and paediatrics and both acute and chronic conditions.

  • Intra Abdominal pain
  • Post Operative pain
  • Non Alcoholic Fatty Liver Disease (NAFLD)
  • Non Alcoholic Steatohepatitis (NASH)
  • Hypercholesterolaemia
  • Type II Diabetes
  • Anaemia
  • Haemophilia
  • Sickle Cell
  • Thrombocytopenia
  • Osteoarthritis
  • Atopic Dermatitis
  • Hidradenitis Suppurativa
  • Psoriasis
  • Crohn’s Disease
  • Ulcerative Colitis
  • Bacterial infection – Sepsis
  • C-Diff
  • Intra-abdominal Infectious Disease
  • Pneumonia
  • Ankylosing Spondylitis
  • Alopecia
  • Asthma
  • Atopic Dermatitis
  • Crohn’s Disease
  • Hidradenitis Suppurativa
  • Lupus
  • Nasal Polyps
  • Psoriasis
  • Psoriatic Arthritis
  • Rheumatoid Arthritis
  • Ulcerative Colitis
  • Vitiligo
  • Alzheimer’s Disease
  • Epilepsy
  • Depression
  • Duchenne Muscular Dystrophy (DMD)
  • Dyskinesia in Cerebral Palsy
  • Migraine
  • Multiple Sclerosis
  • Parkinson’s Disease
  • Schizophrenia
  • Acute Myeloid Leukaemia
  • Basal Cell Carcinoma
  • Bladder Cancer
  • Breast Cancer
  • Colorectal Cancer
  • Gastric Cancer
  • Head & Neck Cancer
  • Liver Cancer
  • Lung Cancer
  • Lymphoma
  • Metastatic Bone Pain
  • Myelofibrosis
  • Mutant Tumours
  • Ovarian Cancer
  • Pancreatic Cancer
  • Prostate Cancer
  • Solid Tumour
  • Treatment Resistance Post Cancer Treatment
  • Urothelial Cancer
  • Asthma
  • COPD
  • Over-active Bladder
  • Pneumonia
  • Urinary Tract Infection
  • Birth Control
  • Interstitial Cystitis
  • STD Prevention
  • Urinary Tract Infection

Do you need to minimise the impact on your clinical trials, or boost patient recruitment in your Covid-19 studies?

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